UFC Fight Night 259: Lopes vs. Silva was a mixed martial arts event produced by the Ultimate Fighting Championship that took place September 13, 2025, at the Frost Bank Center in San Antonio, Texas, United States. A featherweight bout between former UFC Featherweight Championship challenger Diego Lopes and Jean Silva headlined the event.
| Tagline | Noche UFC |
| Release Date: | Sep 13, 2025 |
| Genres: | Action |
| Production Company: | Ultimate Fighting Championship, Zuffa, ESPN |
| Production Countries: | United States of America |
| Casts: | Diego Lopes, Jean Silva, David Martínez, Rob Font, Rafa García, Jared Gordon, Kelvin Gastelum, Dustin Stoltzfus, Alexander Hernandez, Carlos Diego Ferreira, Santiago Luna |
| Status: | Released |
| Budget: | $0 |
| Revenue: | 0 |
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